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Isoniazid overdose in the Cambodian population of Olmsted County, Minnesota.

Authors
  • Blanchard, P D
  • Yao, J D
  • McAlpine, D E
  • Hurt, R D
Type
Published Article
Journal
JAMA
Publication Date
Dec 12, 1986
Volume
256
Issue
22
Pages
3131–3133
Identifiers
PMID: 3783848
Source
Medline
License
Unknown

Abstract

Eight cases of suicidal isoniazid overdose by Cambodian refugees are reviewed. In all patients generalized seizures and metabolic acidosis developed. Treatment included supportive measures and intravenous pyridoxine hydrochloride. There were no deaths. Psychiatric evaluation of each patient revealed usual and extraordinary life and social adjustment stresses. Indochinese immigrants are a subpopulation at risk for isoniazid overdose.

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