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An Isomer-Specific Approach to Endocrine-Disrupting Nonylphenol in Infant Food.

Authors
  • Günther, Klaus1, 2
  • Räcker, Torsten2
  • Böhme, Roswitha1
  • 1 Institute of Nutritional and Food Sciences, Food Chemistry, Rheinische Friedrich-Wilhelms-Universität Bonn , Endenicher Allee 11-13, D-53115 Bonn, Germany. , (Germany)
  • 2 Research Centre Jülich, Institute of Bio- and Geosciences (IBG-2) , D-52425 Jülich, Germany. , (Germany)
Type
Published Article
Journal
Journal of Agricultural and Food Chemistry
Publisher
American Chemical Society
Publication Date
Feb 15, 2017
Volume
65
Issue
6
Pages
1247–1254
Identifiers
DOI: 10.1021/acs.jafc.6b04916
PMID: 28157302
Source
Medline
Keywords
License
Unknown

Abstract

Nonylphenols (NPs) are persistent endocrine disruptors that are priority hazardous substances of the European Union Water Framework Directive. Their presence in the environment has caused growing concern regarding their impact on human health. Recent studies have shown that nonylphenol is ubiquitous in commercially available foodstuffs and is also present in human blood. The isomer distribution of 4-nonylphenol was analyzed by gas chromatography - mass spectrometry in 44 samples of infant food. Our study shows that the distribution of nonylphenol isomers is dependent on the foodstuff analyzed. Although some isomer groups prevail, different distributions are frequent. Variations are even found in the same food group. Nonylphenol is a complex mixture of isomers, and the estrogenic potentials of each of these isomers are very different. Consequently, to determine the potential toxicological impact of NP in food, an isomer-specific approach is necessary.

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