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Isolation of a gastric campylobacter-like organism from the stomach of four rhesus monkeys, and identification as Campylobacter pylori.

Authors
  • Newell, D G
  • Hudson, M J
  • Baskerville, A
Type
Published Article
Journal
Journal of medical microbiology
Publication Date
Sep 01, 1988
Volume
27
Issue
1
Pages
41–44
Identifiers
PMID: 3172170
Source
Medline
License
Unknown

Abstract

Campylobacter-like organisms, isolated from the gastric antrum of Rhesus monkeys, were compared with Campylobacter jejuni and C. pylori. They were similar to C. pylori by light microscopy, in ultrastructural morphology, in enzymic, fatty-acid-methyl-ester, and protein-profile analysis, and in antigenic reactivity with rabbit antisera to C. jejuni and C. pylori and with C. pylori-specific monoclonal antibody. Because this natural infection of the Rhesus monkey is associated with chronic gastritis, resembling the disease in humans colonised with C. pylori, we recommend the animal as a model for the investigation of human gastritis.

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