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The ISNT Rule: How Often Does It Apply to Disc Photographs and Retinal Nerve Fiber Layer Measurements in the Normal Population?

Authors
  • Poon, Linda Yi-Chieh1
  • Solá-Del Valle, David1
  • Turalba, Angela V1
  • Falkenstein, Iryna A1
  • Horsley, Michael1
  • Kim, Julie H1
  • Song, Brian J1
  • Takusagawa, Hana L1
  • Wang, Kaidi2
  • Chen, Teresa C3
  • 1 Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts.
  • 2 Harvard Medical School, Boston, Massachusetts.
  • 3 Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts. Electronic address: [email protected]
Type
Published Article
Journal
American journal of ophthalmology
Publication Date
Dec 01, 2017
Volume
184
Pages
19–27
Identifiers
DOI: 10.1016/j.ajo.2017.09.018
PMID: 28947074
Source
Medline
License
Unknown

Abstract

The ISNT rule is only valid for about a third of disc photographs and less than half of RNFL measurements in normal patients. ISNT rule variants, such as the IST and IS rule, may be considered, as they are valid in more than 70% of patients.

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