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Islet-cell hyperplasia causing hyperinsulinemic hypoglycemia in an adult

Authors
  • Ueda, Yoshihide1
  • Kurihara, Kenji2
  • Kondoh, Tsuyoshi1
  • Okanoue, Toyotake3
  • Chiba, Tsutomu4
  • 1 Departments of Internal Medicine, Uwajima City Hospital, 1-1 Goten-machi, Uwajima, Ehime 798, Japan, JP
  • 2 Departments of Pathology, Uwajima City Hospital, 1-1 Goten-machi, Uwajima, Ehime 798, Japan, JP
  • 3 Departments of Surgery, Uwajima City Hospital, 1-1 Goten-machi, Uwajima, Ehime 798, Japan, JP
  • 4 Division of Gastroenterology and Hepatology, Department of Internal Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan, JP
Type
Published Article
Journal
Journal of Gastroenterology
Publisher
Springer-Verlag
Publication Date
Jan 01, 1998
Volume
33
Issue
1
Pages
125–128
Identifiers
DOI: 10.1007/s005350050057
Source
Springer Nature
Keywords
License
Yellow

Abstract

We report a patient, a 23-year-old man, who had clinical and laboratory findings suggestive of insulinoma. Although imaging studies did not reveal any tumors in the pancreas, distal pancreatectomy was performed because the possibility of small insulinoma could not be completely excluded. Grossly, the surgically removed pancreas did not reveal any tumors. Microscopically, the pancreas exhibited islet cell hyperplasia and nesidioblastosis. To our knowledge, this is the first authentic reported case of islet-cell hyperplasia occurring in a Japanese adult.

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