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ISCR2, another vehicle for bla(VEB) gene acquisition.

Authors
  • Laurent Poirel
  • Pauline D Mugnier
  • Mark A Toleman
  • Timothy R Walsh
  • Melina J Rapoport
  • Alejandro Petroni
  • Patrice Nordmann
Identifiers
DOI: 10.1128/AAC.00414-09
Source
CdV-UPMC
License
Unknown

Abstract

The expanded-spectrum beta-lactamase (ESBL) gene bla(VEB-1), identified worldwide in Enterobacteriaceae and Pseudomonas aeruginosa, is associated with either class 1 integrons or repeated elements. We report here the first association of bla(VEB-1a) with the insertion sequence ISCR2 in six Acinetobacter species isolates recovered from Argentina. That genetic structure was likely at the origin of the mobilization of this ESBL gene.

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