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Iron-mediated direct Suzuki-Miyaura reaction: a new method for the ortho-arylation of pyrrole and pyridine.

Authors
  • Wen, Jun
  • Qin, Song
  • Ma, Li-Fang
  • Dong, Liang
  • Zhang, Ji
  • Liu, Shan-Shan
  • Duan, Yi-Shu
  • Chen, Shan-Yong
  • Hu, Chang-Wei
  • Yu, Xiao-Qi
Type
Published Article
Journal
Organic Letters
Publisher
American Chemical Society
Publication Date
Jun 18, 2010
Volume
12
Issue
12
Pages
2694–2697
Identifiers
DOI: 10.1021/ol100838m
PMID: 20481607
Source
Medline
License
Unknown

Abstract

The first example of an iron-mediated direct Suzuki-Miyaura reaction between N-heterocyclic compounds and arylboronic acids is described, and both electron-rich and electron-deficient heteroarenes can be successfully used for the coupling reaction.

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