Affordable Access

Ionophore-mediated Ca2+ countertransport: role of Na+, Li+ or H+ gradient.

Authors
  • Malaisse, V J
  • Anjaneyulu, K
  • Anjaneyulu, R
  • Couturier, E
Type
Published Article
Journal
Molecular and cellular biochemistry
Publication Date
Apr 18, 1980
Volume
30
Issue
2
Pages
67–70
Identifiers
PMID: 6770248
Source
Medline
License
Unknown

Abstract

In an artificial system, the ionophore A23187, which transports Ca2+ but not Na+, is able to mediate the uphill translocation of Ca2+ from one aqueous medium to another across an organic immiscible phase, provided that a Na+, Li+ or H+ gradient is imposed on the system. Therefore, in the process known as Na-Ca countertransport, the downhill influx of Na+ may not be necessary for causing Ca2+ extrusion against its electrochemical gradient.

Report this publication

Statistics

Seen <100 times