The incorporation of uracil-C(14) into macromolecules in Escherichia coli cells is decreased by doses of ionizing radiation when the cells are in very dilute suspension. The decrease results from an action of irradiated medium on the cells, and a similar reaction is observed during the incorporation of thymine (indication of DNA synthesis) and of proline and valine (indicative of protein synthesis). Irradiated medium reduces the formation of beta-galactosidase but does not cause the degradation of DNA.
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This record was last updated on 06/14/2016 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/14245784