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Iodine-125 induces apoptosis via regulating p53, microvessel density, and vascular endothelial growth factor in colorectal cancer.

Authors
  • Ma, Zhenhuan
  • Yang, Yong
  • Yang, Guokai
  • Wan, Jia
  • Li, Guojian
  • Lu, Ping
  • Du, Lingjuan
Type
Published Article
Journal
World Journal of Surgical Oncology
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Jan 01, 2014
Volume
12
Pages
222–222
Identifiers
DOI: 10.1186/1477-7819-12-222
PMID: 25033896
Source
Medline
License
Unknown

Abstract

The inhibitory mechanisms of iodine on CRC acted through an increase in the level of p53 and a decrease in the level of VEGF, resulting in a decrease of MVD.

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