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Involvement of Ca2+ sensitization in ropivacaine-induced contraction of rat aortic smooth muscle.

Authors
  • Yu, Jingui
  • Tokinaga, Yasuyuki
  • Kuriyama, Toshiyuki
  • Uematsu, Nobuhiko
  • Mizumoto, Kazuhiro
  • Hatano, Yoshio
Type
Published Article
Journal
Anesthesiology
Publication Date
Sep 01, 2005
Volume
103
Issue
3
Pages
548–555
Identifiers
PMID: 16129980
Source
Medline
License
Unknown

Abstract

These findings demonstrated that PKC-, Rho kinase-, and p44/42 MAPK-mediated Ca2+-sensitization mechanisms are involved in the ropivacaine-induced biphasic contraction of rat aortic smooth muscle.

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