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In vivo cardiac glucose metabolism in the high-fat fed mouse: Comparison of euglycemic-hyperinsulinemic clamp derived measures of glucose uptake with a dynamic metabolomic flux profiling approach.

Authors
  • Kowalski, Greg M
  • De Souza, David P
  • Risis, Steve
  • Burch, Micah L
  • Hamley, Steven
  • Kloehn, Joachim
  • Selathurai, Ahrathy
  • Lee-Young, Robert S
  • Tull, Dedreia
  • O'Callaghan, Sean
  • McConville, Malcolm J
  • Bruce, Clinton R
Type
Published Article
Journal
Biochemical and Biophysical Research Communications
Publisher
Elsevier
Publication Date
Aug 07, 2015
Volume
463
Issue
4
Pages
818–824
Identifiers
DOI: 10.1016/j.bbrc.2015.06.019
PMID: 26086096
Source
Medline
Keywords
License
Unknown

Abstract

Under experimental conditions which closely mimic the postprandial state, the insulin resistant mouse heart retains the ability to stimulate glucose metabolism.

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