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Investigations of factors influencing the prognosis of colon cancer.

Authors
  • Gardner, B
  • Feldman, J
  • Spivak, Y
  • Panetta, T
  • Fleischer, J
  • Kasamblides, E
  • Higgins, E
Type
Published Article
Journal
The American Journal of Surgery
Publisher
Elsevier
Publication Date
Jun 01, 1987
Volume
153
Issue
6
Pages
541–544
Identifiers
PMID: 3592069
Source
Medline
License
Unknown

Abstract

Six hundred sixty patients from Downstate and Hackensack Medical Centers were restaged and reviewed to establish correlations with survival using Cox's proportional hazards model. Age, sex, tumor size, and total nodes examined in patients with involved nodes did not correlate with survival. Tumor depth, number of involved nodes, and total nodes examined in patients with uninvolved nodes did correlate with survival. Patients with metastatic invasion into an adjacent organ with uninvolved nodes had an excellent 5 year survival rate compared with patients who had full-thickness invasion into the serosa with uninvolved nodes. These observations need to be confirmed. The relationship of some of these factors to currently used staging systems has also been discussed.

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