Affordable Access

deepdyve-link deepdyve-link
Publisher Website

Investigations on bactericidal properties of molybdenum-tungsten oxides combinatorial thin film material libraries.

Authors
  • Mardare, Cezarina Cela
  • Hassel, Achim Walter
Type
Published Article
Journal
ACS Combinatorial Science
Publisher
American Chemical Society
Publication Date
Nov 10, 2014
Volume
16
Issue
11
Pages
631–639
Identifiers
DOI: 10.1021/co5000536
PMID: 25330357
Source
Medline
Keywords
License
Unknown

Abstract

A combinatorial thin film material library from the molybdenum-tungsten refractory metals oxides system was prepared by thermal coevaporation, and its structural and morphological properties were investigated after a multiple step heat treatment. A mixture of crystalline and amorphous oxides and suboxides was obtained, as well as surface structuring caused by the enrichment of molybdenum oxides in large grains. It was found that the oxide phases and the surface morphology change as a function of the compositional gradient. Tests of the library antimicrobial activity against E. coli were performed and the antimicrobial activity was proven in some defined compositional ranges. A mechanism for explaining the observed activity is proposed, involving a collective contribution from (i) increased local acidity due to the enrichment in large grains of molybdenum oxides with different stoichiometry and (ii) the release of free radicals from the W18O49 phase under visible light.

Report this publication

Statistics

Seen <100 times