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An investigation of the effect of 2 sedation regimens on patient mood state following upper extremity surgery using local anesthesia.

Authors
Type
Published Article
Journal
AANA journal
Publication Date
Volume
68
Issue
2
Pages
135–140
Identifiers
PMID: 10876460
Source
Medline
License
Unknown

Abstract

Sedation techniques for patients undergoing minor outpatient surgery frequently include a variety of intravenous agents. The present study was designed to look for differential effects of 2 different sedation regimens on perioperative mood states. Twenty-two patients undergoing upper extremity surgery using local anesthesia were randomized to receive either propofol or midazolam intravenously for intraoperative sedation. Subjects were asked to complete a Profile of Mood States survey before and after surgery. The results of this survey were examined for differences in mood between the 2 groups that may be attributable to differences in drug effect. No significant differences were identified between propofol or midazolam regarding their effect on patient mood. Patients in both groups experienced a reduction in perioperative anxiety.

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