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Invasive Fungal Disease, Isavuconazole Treatment Failure, and Death in Acute Myeloid Leukemia Patients / Invasive Fungal Disease, Isavuconazole Treatment Failure, and Death in Acute Myeloid Leukemia Patients.

Authors
  • Bellanger, Anne-Pauline
  • Berceanu, Ana
  • Scherer, Emeline
  • Desbrosses, Yohan
  • Daguindau, Etienne
  • Rocchi, Steffi
  • Millon, Laurence
Publication Date
Sep 01, 2019
Source
HAL-SHS
Keywords
Language
English
License
Unknown
External links

Abstract

We present 2 fatal cases of invasive fungal disease with isavuconazole treatment failure in immunocompromised patients: one with a TR34-L98H azole-resistant Aspergillus fumigatus isolate and the other a Rhizomucor-A. fumigatus co-infection. Such patients probably require surveillance by galactomannan antigen detection and quantitative PCRs for A. fumigatus and Mucorales fungi.

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