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Intravenous Chlorothiazide Versus Enteral Metolazone to Augment Loop Diuretic Therapy in the Intensive Care Unit.

Authors
  • Michaud, Christopher J1
  • Mintus, Kendall C2
  • 1 1 Spectrum Health, Grand Rapids, MI, USA.
  • 2 2 Munson Medical Center, Traverse City, MI, USA.
Type
Published Article
Journal
Annals of Pharmacotherapy
Publisher
SAGE Publications
Publication Date
Apr 01, 2017
Volume
51
Issue
4
Pages
286–292
Identifiers
DOI: 10.1177/1060028016683971
PMID: 28228057
Source
Medline
Keywords
License
Unknown

Abstract

Both CTZ and MET induced significant increases in UOP. CTZ induced a greater and more rapid change and was associated with higher cost and greater need for potassium replacement. Randomized controlled trials are needed to establish whether a preferable thiazide diuretic exists in this setting.

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