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Intraretinal and periretinal pathology in anterior proliferative vitreoretinopathy.

Authors
  • Charteris, David G
  • Downie, John
  • Aylward, G William
  • Sethi, Charanjit
  • Luthert, Philip
Type
Published Article
Journal
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie
Publication Date
Jan 01, 2007
Volume
245
Issue
1
Pages
93–100
Identifiers
PMID: 16612635
Source
Medline
License
Unknown

Abstract

Retinal degeneration and photoreceptor apoptosis occur in retinal detachment complicated by proliferative vitreoretinopathy (PVR), although during the early stages of the process neural retinal cells remain present, suggesting potential for recovery. The intraretinal glial response appears to be centrally involved in the formation of contractile epiretinal membranes. The retina retains the capacity for a degree of functional recovery following surgery for PVR. Surgical separation of anterior epiretinal membranes in PVR may be difficult and incomplete and alternative surgical strategies may be necessary to prevent recurrence.

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