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Intraoperative electron beam treatment for pediatric malignancies: The Ohio State University experience.

Authors
  • Nag, Subir
  • Tippin, Douglas
  • Smith, Shane
  • Bauer, Connie
  • Ruymann, Frederick B
Type
Published Article
Journal
Medical and pediatric oncology
Publication Date
Jun 01, 2003
Volume
40
Issue
6
Pages
360–366
Identifiers
PMID: 12692803
Source
Medline
License
Unknown

Abstract

A boost dose of IOERT allows for reduction in the dose of EBRT, thereby limiting growth-related morbidity without compromising local control or disease-free survival. Except for Wilms tumors, which achieved 100% local control and disease-free survival, adjuvant EBRT is necessary for successful local control and survival in children with soft tissue sarcomas. Based on this study and others, intraoperative irradiation should be considered for inclusion in prospective, multi-institutional trials designed to treat localized malignancies in young children.

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