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Intramuscular administration of 15-methyl-prostaglandin F(2alpha) for induction of labour in patients with intrauterine fetal death or an anencephalic fetus.

Authors
  • Ylikorkala, O
  • Kirkinen, P
  • Järvinen, P A
Type
Published Article
Journal
British journal of obstetrics and gynaecology
Publication Date
Jun 01, 1976
Volume
83
Issue
6
Pages
502–504
Identifiers
PMID: 1276108
Source
Medline
Keywords
License
Unknown

Abstract

11 mothers with intrauterine fetal death and 2 with anencephalic fetus ranging from 23 to 36 weeks gestation received 100 to 250 ug of 15-methyl-PGF2alpha intramuscularly at 2-4 hour intervals to induce labor. The mean delivery time was 7 hours (ranging from 45 minutes to 20 hours), the mean number of injections was 3.1, and the mean dose was 400 ug (ranging from 100-700 g). 10 mothers experienced diarrhea and 3 women vomited but there were no serious side effects. Parity or gestational age was unrelated to the efficacy of 15-me-PGF2alpha.

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