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Intraluminal antibiotic regimen for patients undergoing transrectal needle biopsy of prostate.

Authors
  • Babaian, R J
  • Lowry, W L
  • Finan, B F
Type
Published Article
Journal
Urology
Publisher
Elsevier
Publication Date
Sep 01, 1982
Volume
20
Issue
3
Pages
253–255
Identifiers
PMID: 7123716
Source
Medline
License
Unknown

Abstract

Twenty-five consecutive patients who had an abnormal prostate examination were subjected to transrectal biopsy of the prostate gland. The day prior to biopsy the patients were started on a modification of the Nichols-Condon bowel preparation utilizing only neomycin and erythromycin base. Although none of the patients became febrile, 3 patients had a positive post-biopsy blood culture (2 anaerobic and 1 aerobic). None of the 24 patients with a negative pre-biopsy urine culture had a positive post-biopsy culture. This regimen effectively reduces the reported incidence of both fever (95% confidence limit of 0 to 13.7% for the true proportion) and bacteremia (95% confidence limit of 2.6 to 31.2% for the true proportion).

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