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Intragenic suppression: Stalker, a retrovirus-like transposable element, can compensate for a deficiency at the cut locus of Drosophila melanogaster.

Authors
  • Mogila, V A
  • Ladvishenko, A B
  • Simonova, O B
  • Gerasimova, T I
Type
Published Article
Journal
Genetica
Publication Date
Jan 01, 1992
Volume
86
Issue
1-3
Pages
305–311
Identifiers
PMID: 1334915
Source
Medline
License
Unknown

Abstract

A number of mutations at the cut locus were induced by non-precise excision of a silent P-element insertion which resulted in deletions at the regulatory region of the locus. Unexpectedly, a reversion of one of these mutations was found, which appears as a result of insertion of Stalker (a retrovirus-like mobile element) near the 1.3 kb deletion. Thus an insertion of a retrovirus-like mobile element can suppress the deficiency at the regulatory region of a gene.

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