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Intracerebral hemorrhage despite prophylactic administration of vitamin K in infants--two case reports.

Authors
  • Komatsu, Mika
  • Komatsu, Fuminari
  • Tsugu, Hitoshi
  • Yahiro, Tatsumi
  • Oshiro, Shinya
  • Fujita, Tomoko
  • Yoshimura, Kazuko
  • Inoue, Tooru
Type
Published Article
Journal
Neurologia medico-chirurgica
Publication Date
Jan 01, 2011
Volume
51
Issue
2
Pages
130–133
Identifiers
PMID: 21358157
Source
Medline
License
Unknown

Abstract

The incidence of vitamin K deficiency in infancy has decreased markedly, due to prophylactic administration of vitamin K during the neonatal period. However, vitamin K deficiency bleeding may occur during or after the neonatal period despite prophylactic administration in Japan. Two cases are reported of intracranial hemorrhage associated with coagulopathy in full-term infants who had received prophylactic administration of vitamin K. More reliable methods for prophylactic administration should be established.

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