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Intolerance to ß-blockade in a mouse model of δ-sarcoglycan-deficient muscular dystrophy cardiomyopathy.

Authors
  • Bauer, Ralf
  • Blain, Alison
  • Greally, Elizabeth
  • Bushby, Kate
  • Lochmüller, Hanns
  • Laval, Steve
  • Straub, Volker
  • MacGowan, Guy A
Type
Published Article
Journal
European Journal of Heart Failure
Publisher
Wiley (John Wiley & Sons)
Publication Date
Nov 01, 2010
Volume
12
Issue
11
Pages
1163–1170
Identifiers
DOI: 10.1093/eurjhf/hfq129
PMID: 20675662
Source
Medline
License
Unknown

Abstract

β-Blockers may not necessarily be beneficial in all cardiomyopathies, even when given at an early stage of development. Clinical trials of β-blockers in muscular dystrophy-associated cardiomyopathy may need to stratify patients by genotype.

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