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Intestinal intussusception due to a pyogenic granuloma.

Authors
  • Stojsic, Zorica
  • Brasanac, Dimitrije
  • Kokai, George
  • Vujovic, Dragana
  • Zivanovic, Dragana
  • Boricic, Ivan
  • Bacetic, Dragoljub
Type
Published Article
Journal
The Turkish Journal of Pediatrics
Publisher
The Turkish Journal of Pediatrics
Publication Date
Jan 01, 2008
Volume
50
Issue
6
Pages
600–603
Identifiers
PMID: 19227429
Source
Medline
License
Unknown

Abstract

Pyogenic granuloma (PG), also known as lobular capillary hemangioma, is a benign vascular tumor, most commonly arising on the skin and the oral mucosa. Gastrointestinal localization of PG, except for the oral cavity, is exceptionally rare. We describe a case of ileal PG occurring in a 13-year-old girl, presenting with intestinal obstruction. Histological examination revealed proliferation of capillary-sized vessels, with prominent intravascular component, involving the entire thickness of the intestinal wall. Immunohistochemistry showed positivity for CD31, CD34 and von Willebrand factor, whereas immunostaining for glucose transporter-1 protein (GLUT1) and for human herpes virus 8 (HHV-8) was negative. We suggest that PG should be considered in the differential diagnosis of childhood gastrointestinal polypoid lesions.

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