Affordable Access

Interstitial lung disease in systemic lupus erythematosus.

Authors
  • Cheema, G S
  • Quismorio, F P Jr
Type
Published Article
Journal
Current opinion in pulmonary medicine
Publication Date
Sep 01, 2000
Volume
6
Issue
5
Pages
424–429
Identifiers
PMID: 10958234
Source
Medline
License
Unknown

Abstract

Systemic lupus erythematosis (SLE) is a heterogenous disease of unknown etiology. It is not uncommon to see pleuropulmonary involvement in isolation or along with the involvement of other organ systems in SLE. Pulmonary manifestations of SLE can involve the pleura, lung parenchyma, airways, pulmonary vasculature, and the respiratory muscles. In this review we discuss two important pulmonary manifestations of SLE: acute lupus pneumonitis and diffuse interstitial lung disease. These two conditions have a major impact on the mortality and morbidity of patients with SLE and it is essential to recognize and treat them appropriately. High-resolution computed tomographic scans of the chest and pulmonary function tests help to establish a diagnosis and aid long-term follow-up of these patients. High-dose corticosteroids are the mainstay of treatment for the two conditions, although other agents such as cyclophosphamide, azathioprine, intravenous gamma globulin, and plasmapheresis have been used with varying degrees of success.

Report this publication

Statistics

Seen <100 times