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The interpretation and management of abnormal liver function tests.

Authors
  • Simpson, M A
  • Freshwater, D A
Type
Published Article
Journal
Journal of the Royal Naval Medical Service
Publication Date
Jan 01, 2015
Volume
101
Issue
1
Pages
74–79
Identifiers
PMID: 26292397
Source
Medline
License
Unknown

Abstract

Liver function tests (LFTs) are frequently requested as part of routine health assessments on serving members of the Royal Navy (RN). In common with many investigations there are a number of abnormal results in healthy individuals (0.5 - 9% depending on test and study population). There are established patterns of LFT derangement such as cholestatic derangement, hepatocellular derangement, and failure of synthetic function. There can be indicators to the cause of the derangement by assessing the ratios of elevated assays in relation to one another. This article aims to address the definition, potential causes and further investigation of common patterns of LFT derangement found in primary care in the RN.

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