Interleukins and atherosclerosis: a dysfunctional family grows.
Department of Medicine, Division of Endocrinology, Metabolism & Lipid Research, Washington University, St. Louis, MO 63110, USA.
- Published Article
- Publication Date
Nov 05, 2013
Atherosclerosis is driven by the release of cytokines from macrophages, and the β isoform of interleukin-1 (IL-1β) is a prime suspect in disease progression. Freigang et al. (2013) now suggest that IL-1α, a close relative, is selectively induced by fatty acids independent of the inflammasome to promote vascular inflammation.
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This record was last updated on 06/09/2018 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/24206661