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Interleukin-10 stiffens the heart.

Authors
  • Cihakova, Daniela1
  • 1 The Johns Hopkins University.
Type
Published Article
Journal
Journal of Experimental Medicine
Publisher
The Rockefeller University Press
Publication Date
Feb 05, 2018
Volume
215
Issue
2
Pages
379–381
Identifiers
DOI: 10.1084/jem.20180049
PMID: 29348198
Source
Medline
License
Unknown

Abstract

Cardiac-resident macrophages are a diverse population of cells that have a critical role in the pathogenesis of heart failure. A new understanding of communication between macrophages and cardiac fibroblasts could lead to novel therapeutic strategies for heart failure with preserved ejection function.

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