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Interlaboratory bilirubin variability.

Authors
  • Schreiner, R L
  • Glick, M R
Type
Published Article
Journal
Pediatrics
Publication Date
Mar 01, 1982
Volume
69
Issue
3
Pages
277–281
Identifiers
PMID: 7063285
Source
Medline
License
Unknown

Abstract

Stabilized liquid quality control sera, some with elevated bilirubin concentrations, were distributed to laboratories for total and conjugated (direct) bilirubin analyses. Interlaboratory variability was high; for example, results ranged from 10.9 to 24.0 mg/100 ml for a serum with a mean bilirubin concentration of 18.1 mg/100 ml. Coefficients of variation were typically 10% to 12% for total bilirubin ad approximately 24% for conjugated bilirubin analyses. It is believed that these stabilized sera, when used as quality control materials, can help reduce the unacceptably large interlaboratory variability found in this study.

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