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Interferon treatment for corneolimbal squamous dysplasia

Authors
  • Hu, Fung-Rong
  • Wu, Ming-Jer
  • Kuo, Sow-Hsong
Type
Published Article
Journal
American Journal of Ophthalmology
Publisher
Elsevier
Publication Date
Jan 01, 1998
Accepted Date
Aug 27, 1997
Volume
125
Issue
1
Pages
118–119
Identifiers
DOI: 10.1016/S0002-9394(99)80252-9
Source
Elsevier
License
Unknown

Abstract

Purpose: To report a patient with corneolimbal squamous dysplasia successfully treated with interferon therapy. Method: A 78-year-old man had a gelatinous and vascularized lesion involving the left cornea and adjacent limbus. Impression cytology studied with periodic acid—Schiff-hematoxylin stain disclosed severe squamous dysplasia. Topical instillation and subconjunctival injection of interferon alpha-2b was instituted. Results: The gelatinous tumor mass involving the cornea and adjacent limbus completely resolved 2 months after interferon treatment. He showed no sign of recurrence during the 10-month follow-up. Conclusion: Interferon therapy may be a therapeutic alternative for treating corneolimbal squamous dysplasia.

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