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Interferon, IL-2 and Other Cytokines

Authors
  • Buchbinder, Elizabeth I.
  • McDermott, David F.
Type
Published Article
Journal
Hematology/Oncology Clinics of North America
Publisher
Elsevier
Publication Date
Jan 01, 2014
Identifiers
DOI: 10.1016/j.hoc.2014.02.001
Source
Elsevier
Keywords
License
Unknown

Abstract

Cytokines are a diverse group of signaling molecules with immunomodulatory activity. This chapter will review the application of cytokine therapy in melanoma with a focus on Interferon-α and Interleukin-2. In addition it will address the clinical considerations of these therapies including patient selection, reduction in toxicity and combination regimens.

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