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Interferon-gamma inducible protein 10 as a biomarker for active tuberculosis and latent tuberculosis infection in children: a case-control study.

Authors
  • Alsleben, Neele
  • Ruhwald, Morten
  • Rüssmann, Holger
  • Marx, Florian M
  • Wahn, Ulrich
  • Magdorf, Klaus
Type
Published Article
Journal
Scandinavian Journal of Infectious Diseases
Publisher
Informa UK (Taylor & Francis)
Publication Date
Apr 01, 2012
Volume
44
Issue
4
Pages
256–262
Identifiers
DOI: 10.3109/00365548.2011.632644
PMID: 22103555
Source
Medline
License
Unknown

Abstract

IP-10 and IFN-γ were both induced with antigen stimulation in blood from children in the TB and LTBI groups, in contrast to the NTM and RTI groups. Compared to IFN-γ the IP-10 levels were higher and IP-10 was released independently of age. IP-10 therefore may represent an additional biomarker in the paediatric population.

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