Interfacial water and its potential role in the function of sericin against biofouling.
Departamento de Madera, Celulosa y Papel, Universidad de Guadalajara , Zapopan , Jalisco , Mexico.
Instituto Transdiciplinar de Investigación y Servicios/Departamento de Madera, Celulosa y Papel, Universidad de Guadalajara , Zapopan , Jalisco , México.
Department of Bioengineering, University of Washington , Seattle , WA , USA.
- Published Article
Informa UK (Taylor & Francis)
- Publication Date
Aug 01, 2019
Silk sericin is a globular protein whose resistance against fouling is important for applications in biomaterials and water-purification membranes. Here it is shown how sericin generates a water-exclusion zone that may facilitate antifouling behavior. Negatively charged microspheres were used to mimic the surface charge and hydrophobic domains in bacteria. Immersed in water, regenerated silk sericin formed a 100-µm-sized exclusion zone (for micron-size foulants), along with a proton gradient with a decrease of >2 pH-units. Thus, when in contact with sericin, water molecules near the surface restructure to form a physical exclusionary barrier that might prevent biofouling. The decreased pH turns the aqueous medium unviable for neutrophilic bacteria. Therefore, resistance to biofouling seems explainable, among other factors, on the basis of water-exclusionary phenomena. Furthermore, sericin may play a role in triggering the fibroin assembly process by lowering the pH to the required value.
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This record was last updated on 11/01/2019 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/31468985