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Intercellular adhesion molecule-1 regulation in the canine lung after cardiopulmonary bypass.

Authors
Type
Published Article
Journal
Journal of Thoracic and Cardiovascular Surgery
0022-5223
Publisher
American Association for Thoracic Surgery
Publication Date
Volume
115
Issue
3
Identifiers
PMID: 9535458
Source
Medline
License
Unknown

Abstract

Cardiopulmonary bypass resulted in intercellular adhesion molecule-1 induction in the canine lung during recovery. An increased expression of intercellular adhesion molecule-1 protein in the lung was associated with an increased accumulation of neutrophils in affected animals. Thus intercellular adhesion molecule-1 expression may serve as a mechanism that predisposes the lungs to inflammatory cell-mediated injury postoperatively.

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