Affordable Access

Intercellular adhesion molecule-1 regulation in the canine lung after cardiopulmonary bypass.

Authors
  • Dreyer, W J
  • Burns, A R
  • Phillips, S C
  • Lindsey, M L
  • Jackson, P
  • Kukielka, G L
Type
Published Article
Journal
Journal of Thoracic and Cardiovascular Surgery
Publisher
American Association for Thoracic Surgery
Publication Date
Mar 01, 1998
Volume
115
Issue
3
Identifiers
PMID: 9535458
Source
Medline
License
Unknown

Abstract

Cardiopulmonary bypass resulted in intercellular adhesion molecule-1 induction in the canine lung during recovery. An increased expression of intercellular adhesion molecule-1 protein in the lung was associated with an increased accumulation of neutrophils in affected animals. Thus intercellular adhesion molecule-1 expression may serve as a mechanism that predisposes the lungs to inflammatory cell-mediated injury postoperatively.

Report this publication

Statistics

Seen <100 times