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Interactions of quantum dots with donor blood erythrocytes in vitro.

Authors
  • Pleskova, S N
  • Pudovkina, E E
  • Mikheeva, E R
  • Gorshkova, E N
Type
Published Article
Journal
Bulletin of experimental biology and medicine
Publication Date
Jan 01, 2014
Volume
156
Issue
3
Pages
384–388
Identifiers
DOI: 10.1007/s10517-014-2355-x
PMID: 24771382
Source
Medline
License
Unknown

Abstract

The effects of quantum dots CdSe/ZnS-mercaptopropionic acid, (CdSe/CdZnS)ZnS-polyT, and CdSeCdSZnS/polyT/SiO2-NH2 on human erythrocytes were studied. The nanomaterials reduced signifi cantly the erythrocyte sedimentation rate and modified the erythrocyte membrane resistance to induced (acid and hypo-osmotic) hemolysis. Evaluation of the erythrocyte morphology by atomic force microscopy in the control and after exposure to quantum dots showed significant differences in erythrocyte size and changes in their morphology as a result of exposure to the nanomaterials.

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