Affordable Access

Interaction of opiate peptide and noradrenalin systems: light microscopic studies.

Authors
  • Watson, S J
  • Richard, C W 3rd
  • Ciaranello, R D
  • Barchas, J D
Type
Published Article
Journal
Peptides
Publisher
Elsevier
Publication Date
Jan 01, 1980
Volume
1
Issue
1
Pages
23–30
Identifiers
PMID: 7017618
Source
Medline
License
Unknown

Abstract

In this light microscopic immunocytochemical study beta-Endorphin (beta-END), leu-enkephalin and dopamine-beta hydroxylase (DBH) antisera are used to obtain an overview of the interaction of the noradrenergic and opiate peptide systems in brain. Serial brain areas were analyzed for DBH and then for beta-END or leu-enkephalin. Several areas were evaluated for cell and fiber interactions between these systems. The areas of richest possible contact between beta-END and DBH positive systems include the rostral locus coeruleus region, the periaqueductal grey, possibly the dorsal thalamus, the paraventricular hypothalamus and the arcuate nucleus. Enkephalin cells and fibers were seen surrounding the locus coeruleus throughout its length with a few fibers in the nucleus itself.

Report this publication

Statistics

Seen <100 times