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[Interaction evaluation between APOE epsilon 4 alleles and hippocampal atrophy. Preliminary communication].

Authors
  • Gołebiowski, M
  • Styczyńska, M
  • Pfeffer, A
  • Barcikowska, M
  • Cieszanowski, A
Type
Published Article
Journal
Neurologia i neurochirurgia polska
Publication Date
Jan 01, 2001
Volume
35
Issue
5
Pages
815–820
Identifiers
PMID: 11873594
Source
Medline
License
Unknown

Abstract

In CT images the atrophy of medial parts of temporal lobes was evaluated in 60 patients with Alzheimer-type dementia. In the genotype of 30 patients at least one APOE epsilon 4 allele was identified, the other 30 patients served as the control group. The results of in vivo measurements of temporal lobe atrophy in the examined patients did not show statistically significant relations with APOE genotype which was probably due to entirely different nature and application of both tests.

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