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Interaction between the serotonin and dopamine systems in humans: preliminary findings.

Authors
  • Castrogiovanni, P
  • Di Muro, A
  • Maremmani, I
  • Perossini, M
  • Marazziti, D
Type
Published Article
Journal
Brain Research
Publisher
Elsevier
Publication Date
Dec 11, 1989
Volume
504
Issue
1
Pages
129–131
Identifiers
PMID: 2598007
Source
Medline
License
Unknown

Abstract

The availability of peripheral tools, such as platelet [3H]-imipramine binding and electroretinogram b-wave amplitude, for investigating serotonin and dopamine systems respectively, prompted us to explore the possible relationships between these two systems in a group of 8 healthy drug-free volunteers. The results showed a significant correlation between the peripheral parameters of serotonin and dopamine systems and underline the importance of studying different neurotransmitters at the same time in humans.

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