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Interaction Between 2 Nutraceutical Treatments and Host Immune Status in the Pediatric Critical Illness Stress-Induced Immune Suppression Comparative Effectiveness Trial.

Authors
  • Carcillo, Joseph A1
  • Dean, J Michael2
  • Holubkov, Richard2
  • Berger, John3
  • Meert, Kathleen L4
  • Anand, Kanwaljeet J S5
  • Zimmerman, Jerry J6
  • Newth, Christopher J L7
  • Harrison, Rick8
  • Burr, Jeri2
  • Willson, Douglas F9
  • Nicholson, Carol10
  • Bell, Michael J1
  • Berg, Robert A11
  • Shanley, Thomas P12
  • Heidemann, Sabrina M4
  • Dalton, Heidi13
  • Jenkins, Tammara L10
  • Doctor, Allan14
  • Webster, Angie2
  • And 1 more
  • 1 1 Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • 2 2 University of Utah, Salt Lake City, Utah, USA.
  • 3 3 Children's National Medical Center, Washington, DC, USA.
  • 4 4 Children's Hospital of Michigan, Detroit, Michigan, USA.
  • 5 5 Le Bonheur Children's Hospital, Memphis, Tennessee, USA.
  • 6 6 Seattle Children's Hospital, Seattle, Washington, USA.
  • 7 7 Children's Hospital Los Angeles, Los Angeles, California, USA.
  • 8 8 Mattel Children's Hospital at University of California, Los Angeles, California, USA.
  • 9 9 Children's Hospital of Richmond, Richmond, Virginia, USA.
  • 10 10 Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, USA.
  • 11 11 Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
  • 12 12 C. S. Mott Children's Hospital, Ann Arbor, Michigan, USA.
  • 13 13 Phoenix Children's Hospital, Phoenix, Arizona, USA.
  • 14 14 St Louis Children's Hospital, St Louis, Missouri, USA.
Type
Published Article
Journal
JPEN. Journal of parenteral and enteral nutrition
Publication Date
Nov 01, 2017
Volume
41
Issue
8
Pages
1325–1335
Identifiers
DOI: 10.1177/0148607116670377
PMID: 27660289
Source
Medline
Keywords
License
Unknown

Abstract

The science of immune nutrition is more complex than previously thought. Future trial design should consider immune status at the time of trial entry because differential effects of nutraceuticals may be related to this patient characteristic.

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