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Intensive insulin therapy reduces microdialysis glucose values without altering glucose utilization or improving the lactate/pyruvate ratio after traumatic brain injury.

Authors
  • Vespa, Paul
  • Boonyaputthikul, Robert
  • McArthur, David L
  • Miller, Chad
  • Etchepare, Maria
  • Bergsneider, Marvin
  • Glenn, Thomas
  • Martin, Neil
  • Hovda, David
Type
Published Article
Journal
Critical Care Medicine
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Mar 01, 2006
Volume
34
Issue
3
Pages
850–856
Identifiers
PMID: 16505665
Source
Medline
License
Unknown

Abstract

Intensive insulin therapy results in a net reduction in microdialysis glucose and an increase in microdialysis glutamate and lactate/pyruvate without conveying a functional outcome advantage.

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