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Intensive conventional insulin therapy for type II diabetes. Metabolic effects during a 6-mo outpatient trial.

Authors
  • Henry, R R
  • Gumbiner, B
  • Ditzler, T
  • Wallace, P
  • Lyon, R
  • Glauber, H S
Type
Published Article
Journal
Diabetes Care
Publisher
American Diabetes Association
Publication Date
Jan 01, 1993
Volume
16
Issue
1
Pages
21–31
Identifiers
PMID: 8422777
Source
Medline
License
Unknown

Abstract

Intensive CIT, when combined with CBG measurements, can be used to rapidly improve glycemic control in type II diabetes without development of unacceptable hypoglycemia. This degree of metabolic improvement, however, requires large doses of exogenous insulin to overcome peripheral insulin resistance and results in greater hyperinsulinemia with progressive weight gain.

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