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Intensity-modulated versus 3-dimensional conformal radiotherapy in the definitive treatment of esophageal cancer: comparison of outcomes and acute toxicity.

Authors
  • Haefner, Matthias Felix1, 2
  • Lang, Kristin3, 4
  • Verma, Vivek5
  • Koerber, Stefan Alexander3, 4
  • Uhlmann, Lorenz6
  • Debus, Juergen3, 4
  • Sterzing, Florian4, 7
  • 1 Department of Radiation Oncology, University Hospital of Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany. [email protected] , (Germany)
  • 2 National Center for Radiation Research in Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO), Im Neuenheimer Feld 400, 69120, Heidelberg, Germany. [email protected] , (Germany)
  • 3 Department of Radiation Oncology, University Hospital of Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany. , (Germany)
  • 4 National Center for Radiation Research in Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO), Im Neuenheimer Feld 400, 69120, Heidelberg, Germany. , (Germany)
  • 5 Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE, USA.
  • 6 Institute of Medical Biometry and Informatics (IMBI), University of Heidelberg, Im Neuenheimer Feld 130.3, 69120, Heidelberg, Germany. , (Germany)
  • 7 Department of Radiation Oncology, Hospital Kempten, Robert-Weixler-Strasse 50, 87439, Kempten, Germany. , (Germany)
Type
Published Article
Journal
Radiation Oncology
Publisher
Springer (Biomed Central Ltd.)
Publication Date
Aug 15, 2017
Volume
12
Issue
1
Pages
131–131
Identifiers
DOI: 10.1186/s13014-017-0863-3
PMID: 28810885
Source
Medline
Keywords
License
Unknown

Abstract

When comparing 3DCRT- versus IMRT-based dCRT, no survival benefits were observed. However, we found a lower local recurrence rate in the IMRT group potentially owing to dose-escalation. Prospective data are needed to verify the presented results herein.

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