Integrating chemical and mechanical signals in neural crest cell migration.
Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK.
Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK. Electronic address: [email protected]
- Published Article
Current opinion in genetics & development
- Publication Date
Aug 01, 2019
Neural crest cells are a multipotent embryonic stem cell population that migrate large distances to contribute a variety of tissues. The cranial neural crest, which contribute to tissues of the face and skull, undergo collective migration whose movement has been likened to cancer metastasis. Over the last few years, a variety of mechanisms for the guidance of collective cranial neural crest cell migration have been described: mostly chemical, but more recently mechanical. Here we review these different mechanisms and attempt to integrate them to provide a unified model of collective cranial neural crest cell migration. Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.
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This record was last updated on 11/21/2019 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/31306988