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[Insulitis--new findings on the role of genetic and external factors].

Authors
  • Vondra, K1
  • Stolba, P
  • Zamrazil, V
  • 1 Endokrinologický ústav, Praha.
Type
Published Article
Journal
Casopis lekaru ceskych
Publication Date
Nov 01, 1991
Volume
130
Issue
18-19
Pages
529–533
Identifiers
PMID: 1764714
Source
Medline
License
Unknown

Abstract

The autoimmune process focused on B-cells of the islets of Langerhans and leading gradually to their destruction and the development of type I diabetes takes place under the morphological picture of insulitis. The disease affects genetically predisposed individuals. At the end of the eighties knowledge was greatly expanded due to methods of molecular genetics. The majority of authors assumes that in the pathogenesis of insulitis also environmental factors participate. More detailed information is provided on chemical compounds, nutritive substances and viruses.

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