Insulin-like growth factor binding protein-1 in NIDDM: relationship with the insulin resistance syndrome.
- Published Article
- Publication Date
Feb 01, 1999
In NIDDM, concentrations of IGFBP-1 are related to those of insulin, insulin sensitivity, serum lipoproteins and PAI-1 activity. The relationship between concentrations of IGFBP-1 and HDL-cholesterol is not explained by insulin. Concentrations of IGF-1 are linked to HDL-cholesterol, and this is not explained by levels of IGFBP-1. IGFBP-1 concentrations were related to PAI-1 activity, and this may be explained by insulin, which regulates the production of IGFBP-1 and PAI-1.
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The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/10396366