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Insulin attenuates the systemic inflammatory response to thermal trauma.

Authors
  • Jeschke, Marc G1
  • Einspanier, Ralf
  • Klein, Dagmar
  • Jauch, Karl-Walter
  • 1 Klinik und Poliklinik für Chirurgie. Klinikum der Universität Regensburg, Germany. [email protected] , (Germany)
Type
Published Article
Journal
Molecular medicine (Cambridge, Mass.)
Publication Date
Aug 01, 2002
Volume
8
Issue
8
Pages
443–450
Identifiers
PMID: 12435855
Source
Medline
License
Unknown

Abstract

Our data provide insight that insulin attenuates the inflammatory response by decreasing the pro- inflammatory and increasing the anti-inflammatory cas-cade, thereby restoring systemic homeostasis, which has been shown critical for organ function and survival in critically ill patients.

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