Affordable Access

deepdyve-link
Publisher Website

Insufficiency of positive airway pressure treatment on increased mean platelet volume: a prospective controlled study in patients with obstructive sleep apnea syndrome.

Authors
  • Ulusoy, Bülent1
  • Oğuzhan, Tolga2
  • Akyol, Mesut3
  • Bozdemir, Kazım4
  • Çiftçi, Bülent5
  • Korkmaz, Mehmet Hakan4
  • 1 Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Selçuk University, 42075, Konya, Turkey. [email protected] , (Turkey)
  • 2 Department of Otorhinolaryngology-Head and Neck Surgery, Fatih Medical Park Hospital, Istanbul, Turkey. , (Turkey)
  • 3 Department of Biostatistics, Faculty of Medicine, Yıldırım Beyazıt University, Ankara, Turkey. , (Turkey)
  • 4 Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Yıldırım Beyazıt University, Ankara, Turkey. , (Turkey)
  • 5 Department of Pulmonary Disease, Bozok University, Yozgat, Turkey. , (Turkey)
Type
Published Article
Journal
Sleep And Breathing
Publisher
Springer-Verlag
Publication Date
Sep 01, 2020
Volume
24
Issue
3
Pages
885–891
Identifiers
DOI: 10.1007/s11325-019-01918-z
PMID: 31392572
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

To analyze the association between obstructive sleep apnea syndrome (OSAS) and some hematological variables such as mean platelet volume (MPV), platelet distribution width (PDW), and the impact of positive airway pressure (PAP) treatment on these parameters. The participants of the present prospective study consist of 36 OSAS patients diagnosed with polysomnography and recommended PAP treatment and 30 healthy members as the control group. Complete blood analyses were conducted to the patient group twice; before the initiation of the PAP treatment and 1 month after regular PAP use. The control group was administered a complete blood analyses only once. Patient and control group were compared in terms of various parameters such as MPV, PDW, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), white blood cell (WBC) values, and platelet counts. MPV value of the patient group was before and after PAP treatment significantly higher than the control group (respectively; Z = 2.246; p = 0.025, and Z = 2.033; p = 0.042). However, there were no statistically significant differences in the values before and after PAP treatment in the patient group (Z = 0.727; p = 0.467). In terms of platelet numbers and PDW values, no significant differences were determined (p > 0.05). MPV value was significantly elevated in OSAS patients. However, the 1 month of PAP treatment was insufficient in decreasing elevated MPV values.

Report this publication

Statistics

Seen <100 times