Affordable Access

deepdyve-link
Publisher Website

An insight on medicinal attributes of 1,2,4-triazoles.

Authors
  • Aggarwal, Ranjana1
  • Sumran, Garima2
  • 1 Department of Chemistry, Kurukshetra University, Kurukshetra, 136 119, India; CSIR-National Institute of Science Technology and Development Studies, New Delhi, India. Electronic address: [email protected] , (India)
  • 2 Department of Chemistry, D. A. V. College (Lahore), Ambala City, 134 003, Haryana, India. Electronic address: [email protected] , (India)
Type
Published Article
Journal
European journal of medicinal chemistry
Publication Date
Nov 01, 2020
Volume
205
Pages
112652–112652
Identifiers
DOI: 10.1016/j.ejmech.2020.112652
PMID: 32771798
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

The present review aims to summarize the pharmacological profile of 1,2,4-triazole, one of the emerging privileged scaffold, as antifungal, antibacterial, anticancer, anticonvulsant, antituberculosis, antiviral, antiparasitic, analgesic and anti-inflammatory agents, etc. along with structure-activity relationship. The comprehensive compilation of work carried out in the last decade on 1,2,4-triazole nucleus will provide inevitable scope for researchers for the advancement of novel potential drug candidates having better efficacy and selectivity. Copyright © 2020 Elsevier Masson SAS. All rights reserved.

Report this publication

Statistics

Seen <100 times