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Innovative immunohistochemistry identifies MMP-9 expressing macrophages at the invasive front of murine HCC.

Authors
  • Roderfeld, Martin
  • Rath, Timo
  • Lammert, Frank
  • Dierkes, Christian
  • Graf, Jürgen
  • Roeb, Elke
Type
Published Article
Journal
World Journal of Hepatology
Publisher
Baishideng Publishing Group Co (World Journal of Hepatology)
Publication Date
May 27, 2010
Volume
2
Issue
5
Pages
175–179
Identifiers
DOI: 10.4254/wjh.v2.i5.175
PMID: 21160992
Source
Medline
Keywords
License
Unknown

Abstract

MMP-9 expressing macrophages are involved in matrix remodelling at the invasive tumor front of HCC. The described staining protocol provides a simple yet powerful extension of conventional immuno-histochemistry, facilitating visualization of at least three different antigens plus nuclei in one single histological section.

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